The Committee on the Use of Human Subjects (CUHS) serves as the Institutional Review Board for the Cambridge and Allston campuses at Harvard University. Human subjects research at Harvard University is guided by the ethical principles set forth in the Belmont Report (Ethical Principles and Guidelines for the Protection of Human Subjects of Research). The minimum standards are set by the Department of Health and Human Services regulations at 45 CFR part 46 and the Food and Drug Administration’s regulations at 21 CFR part 50 and 21 CFR part 56.

News & Announcements

Undergraduate Research Ethics Training (URTP) now posted!

October 29, 2019

The Undergraduate Research Training Program (URTP) is a comprehensive platform to create better prepared undergraduate researchers.  As part of the program, in-person training sessions are held at various dates throughout the academic year.  The in-person training sessions are an alternative to the standard online CITI training. The sessions have been developed with students in mind: they are 90 minutes in length, interactive, and developed with enthusiasm and energy. Here are some upcoming dates:

Fall 2019...

Read more about Undergraduate Research Ethics Training (URTP) now posted!

Starting June 1, Data Security Level 3 will require HUIT approval prior to IRB approval

June 4, 2019

Why is this change happening?

As you know, all research that receives a data security level (DSL) assignment of 3, 4, or 5 requires review by HUIT. While HUIT DSL 3 must be reviewed within a one-year time frame, HUIT review of DSL 4 and DSL 5 has been required prior to IRB approval. With the recent changes to the federal regulations governing human subject protections, many studies that received a DSL 3 used the continuing review timepoint as a “due date” for the DSL 3 HUIT review. As continuing review is no longer a requirement for many studies, a working group has been...

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ESTR will be unavailable from 4:00 PM ET on Friday, April 12 until 7:00 AM ET on Monday, April 15.

March 28, 2019

Highlights for this release include:

  • Simplified process for single IRB review and management of participating sites,
  • Improved reference and flagging items for reviewers, and 
  • Updated workspace views.

View the detailed release notes to learn about key changes expected with this update.

Read more about ESTR will be unavailable from 4:00 PM ET on Friday, April 12 until 7:00 AM ET on Monday, April 15.

New Alternative to NIH Online Training Now Available!

October 12, 2018

The National Institutes of Health (NIH) discontinued their very popular online ethics training, “Protecting Human Research Participants” on September 26, 2018. Historically, for study team members that are not affiliated with Harvard University or do not have a Harvard Key, the Harvard University Area (HUA) IRB offered this training as an alternative to completion of the CITI ethics training, as the CITI training is only available to Harvard affiliates. With the discontinuation of the NIH training, non-Harvard affiliates were left with few-to-no options.... Read more about New Alternative to NIH Online Training Now Available!

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