Soon, the system that supports IRB reliance (under the Harvard Catalyst Master IRB Reliance Agreement) will undergo a phased shutdown. The last day to start a new request in the Harvard Catalyst system will be Monday, July 31. Learn more about the decommission process. Harvard Catalyst is now supporting SMART IRB, a national platform for IRB reliance with over 230 participating institutions (and counting). Investigators and study staff may start using SMART IRB’s Online Reliance System to request IRB reliance arrangements for their studies.